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High Speed/ Efficient (Quick response or highly available) Application

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Hi,

I am developing an application in MVC Core.

Now I have some concerns.

I want to develop such high efficient/quick application and the response time of this application will be highest Efficient.

I want something like (ebay or amazon high response/quick/efficient applications) 

Now what are my choices to develop such application?

As per my current knowledge,  I know the following things :

1). I should use Asynchronous.

2).  I should use Signal R

3). I should use optimized/well structured code

4). I should parallel programming

5). What else I can do ?

6). Adding more servers / on Clouds (through cloud computing) 

7). Making more Logic on database side for the database efficiency (through stored procedures).  

8). What if I use Angular 4 ? (Will it enhance something in performance or will just improves the powerful UI bindings ?)

Please guide .

It will be really appreciated if some experts will share their opinion or solution about this.


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